Richard R Drake
Richard Drake is a Professor in the Department of Pharmacology and Immunology at the Medical University of South Carolina and SmartState Endowed Chair in Proteomics. He received his Ph.D. in biochemistry from the University of Kentucky in 1990, and did post-doctoral training with Alan Elbein at the University of Texas Health Science Center at San Antonio in N-linked glycan biosynthesis and glycosyltransferase research. His lab developed the workflows for glycan-targeted mass spectrometry imaging of clinical tissues and biofluids for biomarker discovery and development of new diagnostics. He is a founder of GlycoPath Inc., recently sold to Bruker Corporation, which developed the GlycoTyper antibody array assay platform for rapid clinical analysis of serum and immune cell glycoproteins. This platform has recently been adapted for single cell circulating and therapeutic immune cell multi-omic analysis. Current efforts are in the large scale application of N-glycan MS imaging methods to identify glycan biomarker panels associated with tumor, stroma and immune regions of cancer tissues. The glycan imaging workflows are highly synergistic with emerging multi-modality spatial-omic analysis strategies at the macro and single cell levels.
Abstracts this author is presenting: