Wednesday, 18th September HUPO 2019 - 18th Human Proteome Organization World Congress

• Cellular atlas of the transcriptome and proteome - Kathryn Lilley

Sue Weintraub, UTHSCSA; Michael Hoopmann, ISB

• Reverse Engineering to Identify the Next Therapeutic in Heart Failure with Preserved Ejection Fraction? - Jennifer Van Eyk
• The Use of LC/MS and Bio-orthogonal Chemistry to Study Protein Dynamics in Cardiac Remodeling - John R Yates
• Integrative analysis of plasma proteomes from prediabetes and diabetes progression: An IMI DIRECT study - Jochen M Schwenk
• Systems proteomics of the intermittent fasting response highlights the importance of hnf4a - Mark Larance
• From disease to biology: how quantitative proteomics can resolve the molecular diagnosis of mitochondrial disease patients and provide insights into mitochondrial biology - Daniella H. Hock
• Multi-omic profiling of metabolic dysfunction caused by myocardial ischemia / reperfusion (I/R) injury - Alexander W. Rookyard

• Rapid, sensitive and site-specific phosphoproteome profiling of EGFR signaling by data-independent acquisition - Jesper V Olsen
• Hyper-citrullinated library workflow to support demand-driven correct identification of citrullinated residues - Justyna Fert-Bober
• In Vitro Profiling of Ser/Thr/Tyr Selectivity of Human Protein Kinome - Naoyuki Sugiyama
• Multi-stage discovery of hypermodified peptides and hundreds of post translational modifications from open modification search - Nuno Bandeira
• HUPO Proteome Project Phosphopeptide Challenge Report - Susan Weintraub and Michael Hoopmann
• Global redox proteome and phosphoproteome analysis reveals novel insights into the Insulin Signaling Network - David James

• The International Cancer Proteogenome Consortium (ICPC): innovation and collaboration inspired by the Cancer Moonshot^SM - Ana I Robles
• Large Scale Melanoma Cancer Studies at the European Cancer Moonshot Lund Center in Partnership with Five International Hospitals - Johan Malm
• Proteogenomics of colorectal cancer liver metastases: complementing precision oncology with phenotypic data - René P. Zahedi
• Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma - David J Clark
• Patient-derived cancer model for proteogenomics: Report by ICPC JAPAN team - Tadashi Kondo
• Proteogenomic Characterization of Human Gastric Cancer - Yang Du
• Proteogenomic Analysis of Cancer Point Mutations - A Chromosomal Map - Iulia M. Lazar

• The use of proteomics to identify blood-based protein changes in childhood that are associated with increased risk for later psychosis - Melanie Foecking
• Comparative glycoproteomic analyses of cerebrospinal fluids reveal novel molecular players in Alzheimer’s disease - Lingjun Li
• Autoantibody Profiling of Schizophrenia and related Psychotic Disorders in the Australian National Survey of High Impact Psychosis (SHIP)  - K. Oliver Schubert
• Human brain proteome draft atlas to understand biological function and reference for brain tumour investigations   - Sanjeeva Srivastava
• Proteomic and bioenergetic analyses demonstrate synaptic mitochondrial alterations due to age-related pathologic tau accumulation - Kelly L Stauch
• A Proteomic Atlas of Senescence-Associated Secretomes for Aging Biomarker Development - Nathan Basisty

• Microbiome in diseases and health - Daniel Figeys
• Histidine phosphorylation: a new dimension in the phosphoproteome - Simone Lemeer
• Aligning label-based discovery and global DIA validation proteomics to explore bacterial virulence phenotypes - Stuart J Cordwell
• An unbiased metaproteomic approach to describe the mucosal microbiome of an HIV-exposed African infant cohort - Jonathan M Blackburn
• Methylation throughout the proteome: the methyltransferases tell the story - Joshua J Hamey
• Phosphoproteomic study on Staphylococcus aureus to identify phosphoproteins involved in virulence - Nadine Prust

• How do we make quantitative proteomics quantitative? - Michael MacCoss
• Differential Proteomics and Lipidomics in Niemann-Pick Disease, Type C - Stephanie M. Cologna
• Rapid and robust high throughput cancer proteomics across multiple instruments in a single facility - Phillip J Robinson
• Going Beyond 11: TMTpro 16plex Regents for Higher Quantitative Proteomic Sample Multiplexing - Ryan Bomgarden
• Diapasef: Toward The Ideal Mass Analyzer With Data-Independent Acquisition And Parallel Accumulation – Serial Fragmentation - Gary Kruppa
• Heat and Beat: A one-pot rapid tissue sample preparation for proteomics in under an hour - Dylan Xavier

Julian Uszkoreit, Uni. Bochum; Tim Van Den Bossche, Ghent Univ.

Eric Deutsch, ISB, Juan Antonio Vizcaíno, EBI, Nuno Bandeira, UCSD, Luis Mendoza, ISB

• Onco-proteogenomics: toward a more complete understanding of cancer biology - Bing Zhang
• Pathway-level analysis of comprehensive proteogenomic and phosphoproteomic data  to predict clinical outcomes - Karin Rodland
• Multiplex In-Solution Protein Array (MISPA) for high throughput, quantitative profiling of protein interactions and detection of immune responses to pathogen induced cancers - Joshua Labaer
• Improved Survival Prognostication of Node-Positive Malignant Melanoma Patients applying Shotgun Proteomics Guided by Histopathological Characterization and Genomic data - György Marko-Varga
• Delineating mechanisms that confer resistance to kinase inhibitors in head and neck squamous cell carcinoma and melanoma - Harsha Gowda
• Integrative -Omics Reveals Novel Targets Underlying the Pathomechanisms of Uterine Fibroids and Associated Heavy Menstrual Bleeding - Darragh P O'Brien

• Cellular Cartography at Molecular Detail: in Situ Crosslinking Mass Spectrometry - Juri Rappsilber
• Amine-selective Di-ortho-phthalaldehyde (DOPA) Cross-linking Captured the Conformational Change Associated with the Unfolding of Ribonuclease A - Meng-Qiu Dong
• Crosslinking mass spectrometry analysis of the yeast nucleus reveals extensive protein-protein interactions not detected by systematic two-hybrid or affinity purification-mass spectrometry - Marc Wilkins
• Complex-centric proteome profiling in one day with SEC-SWATH-MS and short gradient analysis - Ben C Collins
• Comprehensive identification of RNA–protein interactions in any organism using orthogonal organic phase separation (OOPS) - Eneko Villanueva
• High-throughput protein-protein interaction profiling for clinical applications - Claudia Martelli

• A Multi-Omic Investigation into the Molecular Signatures of Preeclampsia and Gestational Diabetes Mellitus - Erin S Baker
• The role of lipids in plant stress biology - Ute Roessner
• A 'Systems-omics' Strategy to Uncover the Role of Brain Tissue Derived Exosomal Lipids in Alzheimer’s Disease - Gavin E Reid
• MS-based tissue profiling for assistance on neurosurgery operations of brain cancer - Igor Popov
• Comparative targeted and high-throughput metabolomics workflow of small-volume plasma samples - Stephan Klatt
• Identifying predictive network of lipids and proteins among individuals at high and low risk of coronary artery disease using iOmicsPASS - Hiromi W.L. Koh

• Proximity dependent sensors define a role for HOPS in macropinocytosis-dependent control of cell growth - Anne-Claude Gingras
• Venoms to Drugs - Paul Alewood
• Unveiling protein targets involved in haptenation during allergic contact dermatitis via high resolution mass spectrometry - Wint Wint Phoo
• Reverse chemical proteomics identifies unanticipated human target of anti-malarial drug, Artesunate, for drug repositioning - Sung Min Cho
• Proteome profiling of multiple sclerosis cerebrospinal fluid by data independent acquisition reveals changes in proteins involved in adaptive immunity - David R. Spiciarich
• Thermostable potassium channel-inhibiting neurotoxins in processed scorpion medicinal material revealed by proteomic analysis: implications of its pharmaceutical basis in traditional Chinese medicine - Xiaolu Zhao

• Standardizing the performance of SWATH/DIA-MS software tools for label-free quantification using public repository spectral ion libraries - Robert Moritz
• Development of clinically applicable lung cancer proteome biomarkers for in vitro diagnostics-multivariate index assay - Je-Yoel Cho
• Multidimension lc-ms/ms analysis of csf samples in the biofind cohort for biomarker discovery in Parkinson's disease - Jarrod Marto
• Human complement factor B: a new pancreatic cancer biomarker with multiple functions - YOUNG-KI PAIK
• The eutopic endometrium proteome in endometriosis reveals candidate markers and molecular mechanisms of physiopathology - Charles Pineau
• Phenotyping of multiple biofluids for liquid biomarkers for diagnostics and personalized medicine - Allan Stensballe

• Unraveling protein targets of bioactive small molecules using label-free chemical proteomics - HoJeong Kwon
• An Array of 60,000 Antibodies for Proteome-Scale Antibody Generation and Target Discovery - Sheng-ce Tao
• Proteome-wide detection of cysteine nitrosylation targets and motifs using bioorthogonal cleavable-linker-based enrichment and switch technique (Cys-BOOST) - Ruzanna Mnatsakanyan
• System-wide identification of enzyme substrates by thermal analysis - Amir Ata Saei
• Mass Spectrometry Imaging of RTKi with protein target in human lung cancer tumor xenograft mouse - Tae young Kim
• An enhanced boosting to amplify signal with isobaric labeling (eBASIL) approach toward comprehensive quantitative single-cell proteomics analysis - Tao Liu

• Big Data And Health And World Wide Omics Profiling - Michael Snyder